Chargement en cours...
The crystal structure of a 250-kDa heterotetrameric particle explains inhibition of sheddase meprin β by endogenous fetuin-B
Meprin β (Mβ) is a multidomain type-I membrane metallopeptidase that sheds membrane-anchored substrates, releasing their soluble forms. Fetuin-B (FB) is its only known endogenous protein inhibitor. Herein, we analyzed the interaction between the ectodomain of Mβ (MβΔC) and FB, which stabilizes the e...
Enregistré dans:
| Publié dans: | Proc Natl Acad Sci U S A |
|---|---|
| Auteurs principaux: | , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
National Academy of Sciences
2021
|
| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8040653/ https://ncbi.nlm.nih.gov/pubmed/33782129 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2023839118 |
| Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|