Honokiol Prevents Non-Alcoholic Steatohepatitis-Induced Liver Cancer via EGFR Degradation through the Glucocorticoid Receptor—MIG6 Axis

SIMPLE SUMMARY: Non-alcoholic fatty liver disease (NAFLD) is a major health problem globally linked with the growing prevalence of metabolic syndrome. A subset of patients with NAFLD progress to non-alcoholic steatohepatitis (NASH), which increases the risk of hepatocellular carcinoma (HCC). However...

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Udgivet i:Cancers (Basel)
Main Authors: Okuda, Keiichiro, Umemura, Atsushi, Umemura, Shiori, Kataoka, Seita, Taketani, Hiroyoshi, Seko, Yuya, Nishikawa, Taichiro, Yamaguchi, Kanji, Moriguchi, Michihisa, Kanbara, Yoshihiro, Arbiser, Jack L., Shima, Toshihide, Okanoue, Takeshi, Karin, Michael, Itoh, Yoshito
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2021
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8037653/
https://ncbi.nlm.nih.gov/pubmed/33806040
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers13071515
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