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Quantitative Proteomic Approach Reveals Altered Metabolic Pathways in Response to the Inhibition of Lysine Deacetylases in A549 Cells under Normoxia and Hypoxia

Growing evidence is showing that acetylation plays an essential role in cancer, but studies on the impact of KDAC inhibition (KDACi) on the metabolic profile are still in their infancy. Here, we analyzed, by using an iTRAQ-based quantitative proteomics approach, the changes in the proteome of KRAS-m...

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Dettagli Bibliografici
Pubblicato in:Int J Mol Sci
Autori principali: Martín-Bernabé, Alfonso, Tarragó-Celada, Josep, Cunin, Valérie, Michelland, Sylvie, Cortés, Roldán, Poignant, Johann, Boyault, Cyril, Rachidi, Walid, Bourgoin-Voillard, Sandrine, Cascante, Marta, Seve, Michel
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2021
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8036653/
https://ncbi.nlm.nih.gov/pubmed/33806075
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22073378
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