Physiologic Responses to Dietary Sulfur Amino Acid Restriction in Mice Are Influenced by Atf4 Status and Biological Sex

BACKGROUND: Dietary sulfur amino acid restriction (SAAR) improves body composition and metabolic health across several model organisms in part through induction of the integrated stress response (ISR). OBJECTIVE: We investigate the hypothesis that activating transcription factor 4 (ATF4) acts as a c...

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Veröffentlicht in:J Nutr
Hauptverfasser: Jonsson, William O, Margolies, Nicholas S, Mirek, Emily T, Zhang, Qian, Linden, Melissa A, Hill, Cristal M, Link, Christopher, Bithi, Nazmin, Zalma, Brian, Levy, Jordan L, Pettit, Ashley P, Miller, Joshua W, Hine, Christopher, Morrison, Christopher D, Gettys, Thomas W, Miller, Benjamin F, Hamilton, Karyn L, Wek, Ronald C, Anthony, Tracy G
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2021
Schlagworte:
Biochemical, Molecular, and Genetic Mechanisms
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8030708/
https://ncbi.nlm.nih.gov/pubmed/33512502
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jn/nxaa396
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