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Extravascular fibrinogen in the white matter of Alzheimer’s disease and normal aged brains: implications for fibrinogen as a biomarker for Alzheimer’s disease

The blood–brain barrier (BBB) regulates cerebrovascular permeability and leakage of blood‐derived fibrinogen. Dysfunction of the BBB has been associated with cerebral arteriolosclerosis small vessel disease (SVD) and white matter lesions (WML). Furthermore, BBB dysfunction is associated with the pat...

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Detalhes bibliográficos
Publicado no:Brain Pathol
Main Authors: McAleese, Kirsty E., Graham, Sophie, Dey, Madhurima, Walker, Lauren, Erskine, Daniel, Johnson, Mary, Johnston, Eleanor, Thomas, Alan J., McKeith, Ian G., DeCarli, Charles, Attems, Johannes
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8028661/
https://ncbi.nlm.nih.gov/pubmed/30485582
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bpa.12685
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