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MHC class I-independent activation of virtual memory CD8 T cells induced by chemotherapeutic agent-treated cancer cells

Cancer cells can evade immune recognition by losing major histocompatibility complex (MHC) class I. Hence, MHC class I-negative cancers represent the most challenging cancers to treat. Chemotherapeutic drugs not only directly kill tumors but also modulate the tumor immune microenvironment. However,...

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Vydáno v:Cell Mol Immunol
Hlavní autoři: Wang, Xiaoguang, Waschke, Brittany C., Woolaver, Rachel A., Chen, Samantha M. Y., Chen, Zhangguo, Wang, Jing H.
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8027191/
https://ncbi.nlm.nih.gov/pubmed/32427883
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41423-020-0463-2
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