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Plasticity of distal nephron epithelia from human kidney organoids enables the induction of ureteric tip and stalk.

During development, distinct progenitors contribute to the nephrons versus the ureteric epithelium of the kidney. Indeed, previous human pluripotent stem cell-derived models of kidney tissue either contain nephrons or pattern specifically to the ureteric epithelium. By re-analysing the transcription...

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Библиографические подробности
Опубликовано в: :Cell Stem Cell
Главные авторы: Howden, Sara E., Wilson, Sean B., Groenewegen, Ella, Starks, Lakshi, Forbes, Thomas A, Tan, Ker Sin, Vanslambrouck, Jessica M., Holloway, Emily M., Chen, Yi-Hsien, Jain, Sanjay, Spence, Jason R., Little, Melissa H.
Формат: Artigo
Язык:Inglês
Опубликовано: 2020
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC8026527/
https://ncbi.nlm.nih.gov/pubmed/33378647
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2020.12.001
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