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Quantifying evolutionary importance of protein sites: A Tale of two measures

A key challenge in evolutionary biology is the accurate quantification of selective pressure on proteins and other biological macromolecules at single-site resolution. The evolutionary importance of a protein site under purifying selection is typically measured by the degree of conservation of the p...

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Detalhes bibliográficos
Publicado no:PLoS Genet
Main Authors: Sharir-Ivry, Avital, Xia, Yu
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8026052/
https://ncbi.nlm.nih.gov/pubmed/33826605
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1009476
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