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Insights into the Dynamics of the Human Zinc Transporter ZnT8 by MD Simulations

[Image: see text] ZnT8 is a human zinc(II) transporter expressed at the membrane of secretory granules where it contributes to insulin storage importing zinc ions from the cytosol. In the human population, the two most common ZnT8 variants carry an arginine (R325) or a tryptophan (W325) in position...

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Publicat a:J Chem Inf Model
Autors principals: Sala, Davide, Giachetti, Andrea, Rosato, Antonio
Format: Artigo
Idioma:Inglês
Publicat: American Chemical Society 2021
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8023586/
https://ncbi.nlm.nih.gov/pubmed/33508935
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jcim.0c01139
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