Vildagliptin Attenuates Myocardial Dysfunction and Restores Autophagy via miR-21/SPRY1/ERK in Diabetic Mice Heart

Aim: Vildagliptin (vild) improves diastolic dysfunction and is associated with a lower relative risk of major adverse cardiovascular events in younger patients. The present study aimed to evaluate whether vild prevents the development of diabetic cardiomyopathy in type 2 diabetic mice and identify i...

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Detalhes bibliográficos
Publicado no:Front Pharmacol
Main Authors: Li, Xiaochen, Meng, Cheng, Han, Fei, Yang, Juhong, Wang, Jingyu, Zhu, Yanjuan, Cui, Xiao, Zuo, Minxia, Xu, Jie, Chang, Baocheng
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
Assuntos:
Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8013777/
https://ncbi.nlm.nih.gov/pubmed/33815116
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2021.634365
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