Mutational and biophysical robustness in a prestabilized monobody

The fibronectin type III (FN3) monobody domain is a promising non-antibody scaffold, which features a less complex architecture than an antibody while maintaining analogous binding loops. We previously developed FN3Con, a hyperstable monobody derivative with diagnostic and therapeutic potential. Pre...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:J Biol Chem
Main Authors: Chandler, Peter G., Tan, Li Lynn, Porebski, Benjamin T., Green, James S., Riley, Blake T., Broendum, Sebastian S., Hoke, David E., Falconer, Robert J., Munro, Trent P., Buckle, Malcolm, Jackson, Colin J., Buckle, Ashley M.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2021
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8010708/
https://ncbi.nlm.nih.gov/pubmed/33617878
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jbc.2021.100447
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker