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Inhibition of HERV-K (HML-2) in amyotrophic lateral sclerosis patients on antiretroviral therapy

Reactivation of Human Endogenous Retrovirus K (HERV-K), subtype HML-2, has been associated with pathophysiology of amyotrophic lateral sclerosis (ALS). We aimed to assess the efficacy of antiretroviral therapy in inhibiting HML-2 in patients with ALS and a possible association between the change in...

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Bibliographic Details
Published in:J Neurol Sci
Main Authors: Garcia-Montojo, M, Fathi, S, Norato, G, Smith, B.R, Rowe, D.B, Kiernan, M.C, Vucic, S, Mathers, S, van Eijk, R.P.A, Santamaria, U, Rogers, M-L, Malaspina, A, Lombardi, V, Mehta, P.R, Westeneng, H-J, van den Berg, L.H, A, Al-Chalabi, Gold, J, Nath, A
Format: Artigo
Language:Inglês
Published: 2021
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC8009857/
https://ncbi.nlm.nih.gov/pubmed/33653604
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jns.2021.117358
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