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Intrafibrillar Mineralization Deficiency and Osteogenesis Imperfecta Mouse Bone Fragility

Osteogenesis imperfecta (OI), a brittle bone disease, is known to result in severe bone fragility. However, its ultrastructural origins are still poorly understood. In this study, we hypothesized that deficient intrafibrillar mineralization is a key contributor to the OI induced bone brittleness. To...

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Bibliographische Detailangaben
Veröffentlicht in:J Mech Behav Biomed Mater
Hauptverfasser: Maghsoudi-Ganjeh, Mohammad, Samuel, Jitin, Ahsan, Abu Saleh, Wang, Xiaodu, Zeng, Xiaowei
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2021
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8009844/
https://ncbi.nlm.nih.gov/pubmed/33636677
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmbbm.2021.104377
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