Age and sex effects on FGF23-mediated response to mild phosphate challenge

BACKGROUND: During aging, there is a normal and mild loss in kidney function that leads to abnormalities of the kidney-bone metabolic axis. In the setting of increased phosphorus intake, hyperphosphatemia can occur despite increased concentrations of the phosphaturic hormone FGF23. This is likely fr...

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Bibliographic Details
Published in:Bone
Main Authors: Tippen, Samantha P., Noonan, Megan L., Ni, Pu, Metzger, Corinne E., Swallow, Elizabeth A., Sacks, Spencer A., Chen, Neal X., Thompson, William R., Prideaux, Matthew, Atkins, Gerald J., Moe, Sharon M., Allen, Matthew R., White, Kenneth E.
Format: Artigo
Language:Inglês
Published: 2021
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC8009839/
https://ncbi.nlm.nih.gov/pubmed/33618073
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bone.2021.115885
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