Genetic variation in enhancers modifies cardiomyopathy gene expression and progression

BACKGROUND: Inherited cardiomyopathy associates with a range of phenotype, mediated by genetic and non-genetic factors. Non-inherited cardiomyopathy also displays varying progression and outcomes. Expression of cardiomyopathy genes is under the regulatory control of promoters and enhancers, and huma...

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Bibliographic Details
Published in:Circulation
Main Authors: Gacita, Anthony M., Fullenkamp, Dominic E., Ohiri, Joyce, Pottinger, Tess, Puckelwartz, Megan J., Nobrega, Marcelo A., McNally, Elizabeth M.
Format: Artigo
Language:Inglês
Published: 2021
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC8009836/
https://ncbi.nlm.nih.gov/pubmed/33478249
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCULATIONAHA.120.050432
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