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The MEK1/2 Pathway as a Therapeutic Target in High-Grade Serous Ovarian Carcinoma
SIMPLE SUMMARY: High-grade serous ovarian carcinoma (HGSOC) has poor prognosis for patients due to its high rate of recurrence and acquired resistance to therapy. MEK1/2-ERK1/2 signaling pathway that controls cell proliferation and survival is active in the majority of HGSOC cases, but its functiona...
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| Publicado no: | Cancers (Basel) |
|---|---|
| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
MDPI
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8003094/ https://ncbi.nlm.nih.gov/pubmed/33803586 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers13061369 |
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