FOSL2 promotes VEGF-independent angiogenesis by transcriptionnally activating Wnt5a in breast cancer-associated fibroblasts

Cancer-associated fibroblasts (CAFs), a predominant component of the tumor microenvironment, contribute to aggressive angiogenesis progression. In clinical practice, traditional anti-angiogenic therapy, mainly anti-VEGF, provides extremely limited beneficial effects to breast cancer. Here, we reveal...

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Detalhes bibliográficos
Publicado no:Theranostics
Main Authors: Wan, Xueying, Guan, Shengdong, Hou, Yixuan, Qin, Yilu, Zeng, Huan, Yang, Liping, Qiao, Yina, Liu, Shuiqing, Li, Qiao, Jin, Ting, Qiu, Yuxiang, Liu, Manran
Formato: Artigo
Idioma:Inglês
Publicado em: Ivyspring International Publisher 2021
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7978317/
https://ncbi.nlm.nih.gov/pubmed/33754039
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.55074
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