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Protective low-avidity anti-tumour CD8+ T cells are selectively attenuated by regulatory T cells
OBJECTIVES: Regulatory T cells (Treg) play a major role in the suppression of protective anti-tumour T cell responses. In the CT26 BALB/c murine model of colorectal carcinoma, Tregs differentially suppress responses to two characterised CD8+ T epitopes, AH1 and GSW11, which results in an absence of...
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| Publicat a: | Immunother Adv |
|---|---|
| Autors principals: | , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Oxford University Press
2020
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7958313/ https://ncbi.nlm.nih.gov/pubmed/33748824 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/immadv/ltaa001 |
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