The catalytic subunit of Plasmodium falciparum casein kinase 2 is essential for gametocytogenesis

Casein kinase 2 (CK2) is a pleiotropic kinase phosphorylating substrates in different cellular compartments in eukaryotes. In the malaria parasite Plasmodium falciparum, PfCK2 is vital for asexual proliferation of blood-stage parasites. Here, we applied CRISPR/Cas9-based gene editing to investigate...

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Udgivet i:Commun Biol
Main Authors: Hitz, Eva, Grüninger, Olivia, Passecker, Armin, Wyss, Matthias, Scheurer, Christian, Wittlin, Sergio, Beck, Hans-Peter, Brancucci, Nicolas M. B., Voss, Till S.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2021
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7954856/
https://ncbi.nlm.nih.gov/pubmed/33712726
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s42003-021-01873-0
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