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Cytidine Monophosphate N-Acetylneuraminic Acid Synthetase and Solute Carrier Family 35 Member A1 Are Required for Reovirus Binding and Infection

Engagement of cell surface receptors by viruses is a critical determinant of viral tropism and disease. The reovirus attachment protein σ1 binds sialylated glycans and proteinaceous receptors to mediate infection, but the specific requirements for different cell types are not entirely known. To iden...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Urbanek, Kelly, Sutherland, Danica M., Orchard, Robert C., Wilen, Craig B., Knowlton, Jonathan J., Aravamudhan, Pavithra, Taylor, Gwen M., Virgin, Herbert W., Dermody, Terence S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7944449/
https://ncbi.nlm.nih.gov/pubmed/33087464
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01571-20
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