Selective inhibition of V600E-mutant BRAF gene induces apoptosis in thyroid carcinoma cell lines

PURPOSE: Papillary thyroid cancer (PTC) has a high incidence of BRAF(V600E) mutation. The purpose of this study was to evaluate the potential relationship between thyroiditis and BRAF(V600E) mutation status in patients with PTC. We investigated how a selective inhibitor of BRAF(V600E) PLX4032 affect...

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Bibliografiske detaljer
Udgivet i:Ann Surg Treat Res
Main Authors: Park, Kyoung Sik, Saindane, Madhuri, Yang, Eun Yeol, Jin, TongYi, Rallabandi, Harikrishna Reddy, Heil, Alexander, Nam, Sang Eun, Yoo, Young Bum, Yang, Jung-Hyun, Kim, Jong Bin, Park, Seo-Young, Park, Won Seo, Youn, Yeo-Kyu
Format: Artigo
Sprog:Inglês
Udgivet: The Korean Surgical Society 2021
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Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7943282/
https://ncbi.nlm.nih.gov/pubmed/33748026
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4174/astr.2021.100.3.127
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