Leonurine Promotes the Osteoblast Differentiation of Rat BMSCs by Activation of Autophagy via the PI3K/Akt/mTOR Pathway

BACKGROUND: Leonurine, a major bioactive component from Herba leonuri, has been shown to exhibit anti-inflammatory and antioxidant effects. The aim of this study was to investigate the effect of leonurine on bone marrow-derived mesenchymal stem cells (BMSCs) as a therapeutic approach for treating os...

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Detalhes bibliográficos
Publicado no:Front Bioeng Biotechnol
Main Authors: Zhao, Bingkun, Peng, Qian, Poon, Enoch Hin Lok, Chen, Fubo, Zhou, Rong, Shang, Guangwei, Wang, Dan, Xu, Yuanzhi, Wang, Raorao, Qi, Shengcai
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
Assuntos:
Bioengineering and Biotechnology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7940513/
https://ncbi.nlm.nih.gov/pubmed/33708763
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fbioe.2021.615191
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