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One-step sequence and structure-guided optimization of HIV-1 envelope gp140
Stabilization of the metastable envelope glycoprotein (Env) of HIV-1 is hypothesized to improve induction of broadly neutralizing antibodies. We improved the expression yield and stability of the HIV-1 envelope glycoprotein BG505SOSIP.664 gp140 by means of a previously described automated sequence a...
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| Publicat a: | Curr Res Struct Biol |
|---|---|
| Autors principals: | , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Elsevier
2020
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7939140/ https://ncbi.nlm.nih.gov/pubmed/33688632 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.crstbi.2020.04.001 |
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