Lidocaine Inhibits Myoblast Cell Migration and Myogenic Differentiation Through Activation of the Notch Pathway

PURPOSE: To assess the cellular and molecular effects of lidocaine on muscles/myoblasts. METHODS: Cultured myogenic precursor (C2C12) cells were treated with varying concentrations of lidocaine. RESULTS: Cell viability of C2C12 cells was inhibited by lidocaine in a concentration-dependent manner, wi...

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Detalles Bibliográficos
Publicado en:Drug Des Devel Ther
Main Authors: Ling, Xiangtian, Ma, Xinqi, Kuang, Xielan, Zou, Yuxiu, Zhang, Han, Tang, Han, Du, Han, Zhu, Binbin, Huang, Hao, Xia, Qing, Chen, Minghao, Mao, Danyi, Chen, Dongli, Shen, Huangxuan, Yan, Jianhua
Formato: Artigo
Idioma:Inglês
Publicado: Dove 2021
Assuntos:
Original Research
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7936691/
https://ncbi.nlm.nih.gov/pubmed/33688167
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S290002
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