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LIM and SH3 protein 1 localizes to the leading edge of protruding lamellipodia and regulates axon development

The actin cytoskeleton drives cell motility and is essential for neuronal development and function. LIM and SH3 protein 1 (LASP1) is a unique actin-binding protein that is expressed in a wide range of cells including neurons, but its roles in cellular motility and neuronal development are not well u...

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Veröffentlicht in:Mol Biol Cell
Hauptverfasser: Pollitt, Stephanie L., Myers, Kenneth R., Yoo, Jin, Zheng, James Q.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The American Society for Cell Biology 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7927181/
https://ncbi.nlm.nih.gov/pubmed/32997597
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E20-06-0366
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