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α-Ketoheterocycles Able to Inhibit the Generation of Prostaglandin E(2) (PGE(2)) in Rat Mesangial Cells

Prostaglandin E(2) (PGE(2)) is a key mediator of inflammation, and consequently huge efforts have been devoted to the development of novel agents able to regulate its formation. In this work, we present the synthesis of various α-ketoheterocycles and a study of their ability to inhibit the formation...

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Detalhes bibliográficos
Publicado no:Biomolecules
Main Authors: Psarra, Anastasia, Theodoropoulou, Maria A., Erhardt, Martin, Mertiri, Marina, Mantzourani, Christiana, Vasilakaki, Sofia, Magrioti, Victoria, Huwiler, Andrea, Kokotos, George
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7918003/
https://ncbi.nlm.nih.gov/pubmed/33668480
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biom11020275
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