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α-Ketoheterocycles Able to Inhibit the Generation of Prostaglandin E(2) (PGE(2)) in Rat Mesangial Cells

Prostaglandin E(2) (PGE(2)) is a key mediator of inflammation, and consequently huge efforts have been devoted to the development of novel agents able to regulate its formation. In this work, we present the synthesis of various α-ketoheterocycles and a study of their ability to inhibit the formation...

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Dettagli Bibliografici
Pubblicato in:Biomolecules
Autori principali: Psarra, Anastasia, Theodoropoulou, Maria A., Erhardt, Martin, Mertiri, Marina, Mantzourani, Christiana, Vasilakaki, Sofia, Magrioti, Victoria, Huwiler, Andrea, Kokotos, George
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2021
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7918003/
https://ncbi.nlm.nih.gov/pubmed/33668480
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biom11020275
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