Inhibition of Mitochondrial Dynamics Preferentially Targets Pancreatic Cancer Cells with Enhanced Tumorigenic and Invasive Potential

SIMPLE SUMMARY: Due to their intrinsic aggressiveness, cancer stem cells (CSCs) represent an essential target for the design of effective treatments against pancreatic cancer, one of the deadliest tumors. As pancreatic CSCs are particularly dependent on the activity of their mitochondria, we here fo...

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Pubblicato in:Cancers (Basel)
Autori principali: Courtois, Sarah, de Luxán-Delgado, Beatriz, Penin-Peyta, Laure, Royo-García, Alba, Parejo-Alonso, Beatriz, Jagust, Petra, Alcalá, Sonia, Rubiolo, Juan A., Sánchez, Laura, Sainz, Bruno, Heeschen, Christopher, Sancho, Patricia
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2021
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7914708/
https://ncbi.nlm.nih.gov/pubmed/33572276
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers13040698
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