Inhibition of Mitochondrial Dynamics Preferentially Targets Pancreatic Cancer Cells with Enhanced Tumorigenic and Invasive Potential

SIMPLE SUMMARY: Due to their intrinsic aggressiveness, cancer stem cells (CSCs) represent an essential target for the design of effective treatments against pancreatic cancer, one of the deadliest tumors. As pancreatic CSCs are particularly dependent on the activity of their mitochondria, we here fo...

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Veröffentlicht in:Cancers (Basel)
Hauptverfasser: Courtois, Sarah, de Luxán-Delgado, Beatriz, Penin-Peyta, Laure, Royo-García, Alba, Parejo-Alonso, Beatriz, Jagust, Petra, Alcalá, Sonia, Rubiolo, Juan A., Sánchez, Laura, Sainz, Bruno, Heeschen, Christopher, Sancho, Patricia
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2021
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7914708/
https://ncbi.nlm.nih.gov/pubmed/33572276
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers13040698
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