Anti-tumor and immune modulating activity of T cell induced tumor-targeting effectors (TITE)

Adoptive transfer of Bispecific antibody Armed activated T cells (BATs) showed promising anti-tumor activity in clinical trials in solid tumors. The cytotoxic activity of BATs occurs upon engagement with tumor cells via the bispecific antibody (BiAb) bridge, which stimulates BATs to release cytotoxi...

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Veröffentlicht in:Cancer Immunol Immunother
Hauptverfasser: Thakur, Archana, Kondadasula, Sri Vidya, Ji, Kyungmin, Schalk, Dana L., Bliemeister, Edwin, Ung, Johnson, Aboukameel, Amro, Casarez, Eli, Sloane, Bonnie F., Lum, Lawrence G.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Springer Berlin Heidelberg 2020
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Original Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7914128/
https://ncbi.nlm.nih.gov/pubmed/32865605
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00262-020-02692-8
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