Effect of differentiation, de novo innervation, and electrical pulse stimulation on mRNA and protein expression of Na(+),K(+)-ATPase, FXYD1, and FXYD5 in cultured human skeletal muscle cells

Denervation reduces the abundance of Na(+),K(+)-ATPase (NKA) in skeletal muscle, while reinnervation increases it. Primary human skeletal muscle cells, the most widely used model to study human skeletal muscle in vitro, are usually cultured as myoblasts or myotubes without neurons and typically do n...

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Publicado en:PLoS One
Autores principales: Jan, Vid, Miš, Katarina, Nikolic, Natasa, Dolinar, Klemen, Petrič, Metka, Bone, Andraž, Thoresen, G. Hege, Rustan, Arild C., Marš, Tomaž, Chibalin, Alexander V., Pirkmajer, Sergej
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2021
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7909653/
https://ncbi.nlm.nih.gov/pubmed/33635930
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0247377
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