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Impact of between-tissue differences on pan-cancer predictions of drug sensitivity

Increased availability of drug response and genomics data for many tumor cell lines has accelerated the development of pan-cancer prediction models of drug response. However, it is unclear how much between-tissue differences in drug response and molecular characteristics may contribute to pan-cancer...

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Publicat a:PLoS Comput Biol
Autors principals: Lloyd, John P., Soellner, Matthew B., Merajver, Sofia D., Li, Jun Z.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2021
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7906305/
https://ncbi.nlm.nih.gov/pubmed/33630864
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1008720
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