Human-induced pluripotent stem cells for modelling metabolic perturbations and impaired bioenergetics underlying cardiomyopathies

Normal cardiac contractile and relaxation functions are critically dependent on a continuous energy supply. Accordingly, metabolic perturbations and impaired mitochondrial bioenergetics with subsequent disruption of ATP production underpin a wide variety of cardiac diseases, including diabetic cardi...

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Bibliografiske detaljer
Udgivet i:Cardiovasc Res
Main Authors: Ramachandra, Chrishan J A, Chua, Jasper, Cong, Shuo, Kp, Myu Mai Ja, Shim, Winston, Wu, Joseph C, Hausenloy, Derek J
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2020
Fag:
Developmental Biology and Regeneration Focus
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7898957/
https://ncbi.nlm.nih.gov/pubmed/32365198
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cvr/cvaa125
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