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Immune Checkpoint Inhibitors: Cardiotoxicity in Pre-clinical Models and Clinical Studies

Since the approval of the first immune checkpoint inhibitor (ICI) 9 years ago, ICI-therapy have revolutionized cancer treatment. Lately, antibodies blocking the interaction of programmed cell death protein (PD-1) and ligand (PD-L1) are gaining momentum as a cancer treatment, with multiple agents and...

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Detalhes bibliográficos
Publicado no:Front Cardiovasc Med
Main Authors: Xu, Shirley, Sharma, Umesh C., Tuttle, Cheyanna, Pokharel, Saraswati
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7887301/
https://ncbi.nlm.nih.gov/pubmed/33614750
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcvm.2021.619650
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