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Biomaterial-Based Nanocomposite for Osteogenic Repurposing of Doxycycline
BACKGROUND: Besides its antimicrobial action, doxycycline (DX) has lately been repurposed as a small-molecule drug for osteogenic purposes. However, osteogenic DX application is impeded by its dose-dependent cytotoxicity. Further, high-dose DX impairs cell differentiation and mineralization. PURPOSE...
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| Publicado no: | Int J Nanomedicine |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Dove
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7887185/ https://ncbi.nlm.nih.gov/pubmed/33603371 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S298297 |
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