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Biomaterial-Based Nanocomposite for Osteogenic Repurposing of Doxycycline

BACKGROUND: Besides its antimicrobial action, doxycycline (DX) has lately been repurposed as a small-molecule drug for osteogenic purposes. However, osteogenic DX application is impeded by its dose-dependent cytotoxicity. Further, high-dose DX impairs cell differentiation and mineralization. PURPOSE...

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Dades bibliogràfiques
Publicat a:Int J Nanomedicine
Autors principals: El-Habashy, Salma, Eltaher, Hoda, Gaballah, Ahmed, Mehanna, Radwa, El-Kamel, Amal H
Format: Artigo
Idioma:Inglês
Publicat: Dove 2021
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7887185/
https://ncbi.nlm.nih.gov/pubmed/33603371
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S298297
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