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The Role of the Z-DNA Binding Domain in Innate Immunity and Stress Granules
Both DNA and RNA can maintain left-handed double helical Z-conformation under physiological condition, but only when stabilized by Z-DNA binding domain (ZDBD). After initial discovery in RNA editing enzyme ADAR1, ZDBD has also been described in pathogen-sensing proteins ZBP1 and PKZ in host, as well...
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| Udgivet i: | Front Immunol |
|---|---|
| Main Authors: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Frontiers Media S.A.
2021
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7886975/ https://ncbi.nlm.nih.gov/pubmed/33613567 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.625504 |
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