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Identification of a conserved N‐terminal domain in the first module of ACV synthetases

The l‐δ‐(α‐aminoadipoyl)‐l‐cysteinyl‐d‐valine synthetase (ACVS) is a trimodular nonribosomal peptide synthetase (NRPS) that provides the peptide precursor for the synthesis of β‐lactams. The enzyme has been extensively characterized in terms of tripeptide formation and substrate specificity. The fir...

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Detalhes bibliográficos
Publicado no:Microbiologyopen
Main Authors: Iacovelli, Riccardo, Mózsik, László, Bovenberg, Roel A.L., Driessen, Arnold J.M.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7884236/
https://ncbi.nlm.nih.gov/pubmed/33449449
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mbo3.1145
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