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Cell-to-Cell Adhesion and Neurogenesis in Human Cortical Development: A Study Comparing 2D Monolayers with 3D Organoid Cultures

Organoids (ORGs) are increasingly used as models of cerebral cortical development. Here, we compared transcriptome and cellular phenotypes between telencephalic ORGs and monolayers (MONs) generated in parallel from three biologically distinct induced pluripotent stem cell (iPSC) lines. Multiple read...

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Detalhes bibliográficos
Publicado no:Stem Cell Reports
Main Authors: Scuderi, Soraya, Altobelli, Giovanna G., Cimini, Vincenzo, Coppola, Gianfilippo, Vaccarino, Flora M.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7878838/
https://ncbi.nlm.nih.gov/pubmed/33513360
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2020.12.019
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