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Cell-to-Cell Adhesion and Neurogenesis in Human Cortical Development: A Study Comparing 2D Monolayers with 3D Organoid Cultures

Organoids (ORGs) are increasingly used as models of cerebral cortical development. Here, we compared transcriptome and cellular phenotypes between telencephalic ORGs and monolayers (MONs) generated in parallel from three biologically distinct induced pluripotent stem cell (iPSC) lines. Multiple read...

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Bibliografski detalji
Izdano u:Stem Cell Reports
Glavni autori: Scuderi, Soraya, Altobelli, Giovanna G., Cimini, Vincenzo, Coppola, Gianfilippo, Vaccarino, Flora M.
Format: Artigo
Jezik:Inglês
Izdano: Elsevier 2021
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7878838/
https://ncbi.nlm.nih.gov/pubmed/33513360
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2020.12.019
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