Structural insights and molecular dynamics into the inhibitory mechanism of a Kunitz-type trypsin inhibitor from Tamarindus indica L

Trypsin inhibitors from tamarind seed have been studied in vitro and in preclinical studies for the treatment of obesity, its complications and associated comorbidities. It is still necessary to fully understand the structure and behaviour of these molecules. We purifed this inhibitor, sequenced de...

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Detalhes bibliográficos
Publicado no:J Enzyme Inhib Med Chem
Main Authors: de Medeiros, Amanda Fernandes, de Souza, Beatriz Blenda Pinheiro, Coutinho, Lucas Pinheiro, Murad, Aline Melro, dos Santos, Paula Ivani Medeiros, Monteiro, Norberto de Kássio Vieira, dos Santos, Elizeu Antunes, Maciel, Bruna Leal Lima, de Araújo Morais, Ana Heloneida
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2021
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7875565/
https://ncbi.nlm.nih.gov/pubmed/33491503
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/14756366.2021.1876686
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