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Signaling Control of Antibody Isotype Switching
Class switch recombination (CSR) generates isotype-switched antibodies with distinct effector functions essential for mediating effective humoral immunity. CSR is catalyzed by activation-induced deaminase (AID) that initiates DNA lesions in the evolutionarily conserved switch (S) regions at the immu...
Gorde:
| Argitaratua izan da: | Adv Immunol |
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| Egile Nagusiak: | , |
| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
2019
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7875453/ https://ncbi.nlm.nih.gov/pubmed/30904131 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/bs.ai.2019.01.001 |
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