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Drag-induced directionality switching of kinesin-5 Cin8 revealed by cluster-motility analysis

Directed active motion of motor proteins is a vital process in virtually all eukaryotic cells. Nearly a decade ago, the discovery of directionality switching of mitotic kinesin-5 motors challenged the long-standing paradigm that individual kinesin motors are characterized by an intrinsic directional...

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Библиографические подробности
Опубликовано в: :Sci Adv
Главные авторы: Pandey, Himanshu, Reithmann, Emanuel, Goldstein-Levitin, Alina, Al-Bassam, Jawdat, Frey, Erwin, Gheber, Larisa
Формат: Artigo
Язык:Inglês
Опубликовано: American Association for the Advancement of Science 2021
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7864582/
https://ncbi.nlm.nih.gov/pubmed/33547070
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.abc1687
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