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Quantifying the Stability of Coupled Genetic and Epigenetic Switches With Variational Methods

The Waddington landscape provides an intuitive metaphor to view development as a ball rolling down the hill, with distinct phenotypes as basins and differentiation pathways as valleys. Since, at a molecular level, cell differentiation arises from interactions among the genes, a mathematical definiti...

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Detalhes bibliográficos
Publicado no:Front Genet
Main Authors: Sood, Amogh, Zhang, Bin
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7862759/
https://ncbi.nlm.nih.gov/pubmed/33552146
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2020.636724
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