Can combination therapy with insulin and metformin improve metabolic function of the liver, in type I diabetic patients? An animal model study on CYP2D1 activity

INTRODUCTION: Changes in hepatic clearance and CYP2D1 activity after combination therapy with insulin and metformin in type-1 diabetes and insulin administration in type-2 diabetes was assessed in an animal model. METHODS: Ten male Wistar rats were divided into two groups. Seven days after induction...

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Vydáno v:J Diabetes Metab Disord
Hlavní autoři: Rezai, Sara, Neyshaburinezhad, Navid, Rouini, Mohammadreza, Lavasani, Hoda, H. Ardakani, Yalda
Médium: Artigo
Jazyk:Inglês
Vydáno: Springer International Publishing 2020
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7843674/
https://ncbi.nlm.nih.gov/pubmed/33520876
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s40200-020-00678-y
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