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Akt signaling is activated by TGFβ2 and impacts tenogenic induction of mesenchymal stem cells

BACKGROUND: Tissue engineered and regenerative approaches for treating tendon injuries are challenged by the limited information on the cellular signaling pathways driving tenogenic differentiation of stem cells. Members of the transforming growth factor (TGF) β family, particularly TGFβ2, play a ro...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Stem Cell Res Ther
Hauptverfasser: Theodossiou, Sophia K., Murray, Jett B., Hold, LeeAnn A., Courtright, Jeff M., Carper, Anne M., Schiele, Nathan R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2021
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7836508/
https://ncbi.nlm.nih.gov/pubmed/33499914
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13287-021-02167-2
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