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Akt signaling is activated by TGFβ2 and impacts tenogenic induction of mesenchymal stem cells

BACKGROUND: Tissue engineered and regenerative approaches for treating tendon injuries are challenged by the limited information on the cellular signaling pathways driving tenogenic differentiation of stem cells. Members of the transforming growth factor (TGF) β family, particularly TGFβ2, play a ro...

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Detalhes bibliográficos
Publicado no:Stem Cell Res Ther
Main Authors: Theodossiou, Sophia K., Murray, Jett B., Hold, LeeAnn A., Courtright, Jeff M., Carper, Anne M., Schiele, Nathan R.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7836508/
https://ncbi.nlm.nih.gov/pubmed/33499914
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13287-021-02167-2
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