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Stronger induction of trained immunity by mucosal BCG or MTBVAC vaccination compared to standard intradermal vaccination
BCG vaccination can strengthen protection against pathogens through the induction of epigenetic and metabolic reprogramming of innate immune cells, a process called trained immunity. We and others recently demonstrated that mucosal or intravenous BCG better protects rhesus macaques from Mycobacteriu...
Kaydedildi:
| Yayımlandı: | Cell Rep Med |
|---|---|
| Asıl Yazarlar: | , , , , , , , , , , , , , , , , , , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Elsevier
2021
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7817864/ https://ncbi.nlm.nih.gov/pubmed/33521699 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.xcrm.2020.100185 |
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