The integration of immune checkpoint inhibitors with VEGF targeted agents in advanced gastric and gastroesophageal adenocarcinoma: a review on the rationale and results of early phase trials

Several targeted therapies have shown efficacy in patients with advanced gastric cancer (GC) and gastroesophageal junction adenocarcinoma (GEJC), including anti-angiogenic agents and immune checkpoint inhibitors. Ramucirumab, an anti-VEGFR2 antibody, has shown efficacy in GC, but the benefits are li...

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Bibliografiske detaljer
Udgivet i:J Hematol Oncol
Main Authors: Saeed, Anwaar, Park, Robin, Sun, Weijing
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2021
Fag:
Review
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7802258/
https://ncbi.nlm.nih.gov/pubmed/33436042
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13045-021-01034-0
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