Virus-Mediated Suppression of the Antigen Presentation Molecule MR1

The antigen-presenting molecule MR1 presents microbial metabolites related to vitamin B2 biosynthesis to mucosal-associated invariant T cells (MAIT cells). Although bacteria and fungi drive the MR1 biosynthesis pathway, viruses have not previously been implicated in MR1 expression or its antigen pre...

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Udgivet i:Cell Rep
Main Authors: McSharry, Brian P., Samer, Carolyn, McWilliam, Hamish E.G., Ashley, Caroline L., Yee, Michael B., Steain, Megan, Liu, Ligong, Fairlie, David P., Kinchington, Paul R., McCluskey, James, Abendroth, Allison, Villadangos, Jose A., Rossjohn, Jamie, Slobedman, Barry
Format: Artigo
Sprog:Inglês
Udgivet: 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7798347/
https://ncbi.nlm.nih.gov/pubmed/32130899
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2020.02.017
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